FCGR2B 蛋白
(Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FCGR2B Protein (AA 46-217) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| FCGR2B Protein (AA 46-217) (His-Avi Tag) | 人 | HEK-293 Cells |
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| FCGR2B Protein (AA 40-217) (His tag) | 小鼠 | HEK-293 Cells |
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| FCGR2B Protein (AA 46-224) (His tag) | Cynomolgus | HEK-293 Cells |
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| FCGR2B Protein (AA 45-154) (GST tag) | 人 | 小麦胚 |
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| FCGR2B Protein (AA 46-217) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| FCGR2B Protein (His tag) | 小鼠 | HEK-293 Cells |
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| FCGR2B Protein (His tag) | 大鼠 | HEK-293 Cells |
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| FCGR2B Protein (His-Avi Tag,Biotin) | 小鼠 | HEK-293 Cells |
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| FCGR2B Protein (AA 30-210) (His tag) | 小鼠 | HEK-293 Cells |
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| FCGR2B Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| FCGR2B 蛋白 | 人 | – |
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| FCGR2B Protein (AA 30-210) (His tag) | 小鼠 | Mammalian Cells |
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| FCGR2B 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| FCGR2B Protein (AA 46-217) (His tag) | 人 | HEK-293 Cells |
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| FCGR2B Protein (His tag) | 人 | HEK-293 Cells |
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| FCGR2B Protein (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| FCGR2B Protein (AA 46-217) (His tag) | 人 | HEK-293 Cells |
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| FCGR2B Protein (AA 46-217) (Fc Tag) | 人 | HEK-293 Cells |
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| FCGR2B Protein (AA 32-212) (His tag) | 大鼠 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SEC-HPLC
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SEC-HPLC
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 98 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- BLI (Bio-Layer Interferometry: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Latest Publications for our FCGR2B 蛋白
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
Aliases for FCGR2B 蛋白
Fc fragment of IgG receptor IIb (FCGR2B) 蛋白Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B) 蛋白
Fc receptor, IgG, low affinity IIb (Fcgr2b) 蛋白
Fc fragment of IgG receptor IIb (Fcgr2b) 蛋白
low affinity immunoglobulin gamma Fc region receptor II (LOC100856270) 蛋白
AI528646 蛋白
CD32 蛋白
CD32B 蛋白
F630109E10Rik 蛋白
FCG2 蛋白
FCGR2 蛋白
Fcgr2 蛋白
Fcgr2a 蛋白
FCGR2B 蛋白
FcgRII 蛋白
Fcr-2 蛋白
Fcr-3 蛋白
FCRII 蛋白
FcRII 蛋白
Fc[g]RII 蛋白
IGFR2 蛋白
Ly-17 蛋白
Ly-m20 蛋白
LyM-1 蛋白
Lym-1 蛋白
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