FCAR 抗体
(Fc Fragment of IgA, Receptor For (FCAR))
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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78 results
FCAR
适用: 人
FACS, ELISA, IP
宿主: 兔
Chimeric
14A8
unconjugated
Recombinant Antibody
FCAR
适用: 人
FACS, ELISA, IP
宿主: 小鼠
Monoclonal
14A8
unconjugated
Recombinant Antibody
Latest Publications for our FCAR 抗体
: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).
: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).
: "Intracellular pools of FcalphaR (CD89) in human neutrophils are localized in tertiary granules and secretory vesicles, and two FcalphaR isoforms are found in tertiary granules." in: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 551-8, (2007) (PubMed).
: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." in: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).
: "Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 6, pp. 1764-70, (1992) (PubMed).
Aliases for FCAR 抗体
Fc fragment of IgA receptor (FCAR) 抗体Fc fragment of IgA, receptor for (FCAR) 抗体
CD89 抗体
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