Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs).
Browman, Resek, Zajchowski, Robbins: "Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER." in: Journal of cell science, Vol. 119, Issue Pt 15, pp. 3149-60, (2006) (PubMed).