(ELK3, ETS-Domain Protein (SRF Accessory Protein 2) (ELK3))
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation\; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by RefSeq, Jul 2008].
Kim, Park, Oh, Cho, Park, Park: "ELK3 expressed in lymphatic endothelial cells promotes breast cancer progression and metastasis through exosomal miRNAs." in: Scientific reports, Vol. 9, Issue 1, pp. 8418, (2019) (PubMed).
Kim, Kim, Oh, Kim, Park: "ELK3-GATA3 axis modulates MDA-MB-231 metastasis by regulating cell-cell adhesion-related genes." in: Biochemical and biophysical research communications, Vol. 498, Issue 3, pp. 509-515, (2018) (PubMed).
Yang, Schramek, Adam, Keyes, Wang, Zheng, Fuchs: "ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas." in: eLife, Vol. 4, pp. e10870, (2016) (PubMed).
Robertson, Wasylyk, Ye, Jung, Wasylyk: "The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response." in: PLoS ONE, Vol. 9, Issue 11, pp. e113050, (2014) (PubMed).
Aliases for ELK3 抗体
ELK3, member of ETS oncogene family (Elk3) 抗体 ELK3, ETS transcription factor L homeolog (elk3.L) 抗体 ELK3, ETS transcription factor (ELK3) 抗体 ELK3, ETS transcription factor (Elk3) 抗体 ELK3, ETS-domain protein (elk3) 抗体 D430049E23Rik 抗体 Erp 抗体 erp 抗体 ERP 抗体 Etrp 抗体 Net 抗体 NET 抗体 Sap-2 抗体 sap2 抗体 SAP2 抗体 si:ch211-172b12.2 抗体 si:dkey-201e17.1 抗体 zgc:198153 抗体 zgc:198183 抗体