Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009].
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Aliases for Elastase 3B 抗体
chymotrypsin like elastase family member 3B (CELA3B) 抗体 chymotrypsin-like elastase family, member 3B (Cela3b) 抗体 elastase 3B, pancreatic (ela3b) 抗体 proproteinase E (LOC478196) 抗体 chymotrypsin-like elastase family, member 3B (CELA3B) 抗体 chymotrypsin like elastase family member 3B L homeolog (cela3b.L) 抗体 chymotrypsin-like elastase family member 3B (LOC100717936) 抗体 chymotrypsin-like elastase family member 3B (LOC100071692) 抗体 0910001F22Rik 抗体 2310074F01Rik 抗体 AI504000 抗体 CBPP 抗体 Cela3b 抗体 CELA3B 抗体 E1 抗体 EL-1 抗体 ELA1 抗体 Ela3 抗体 ELA3B 抗体 Ela3b 抗体 ela3b 抗体 MGC82867 抗体