EGLN1 抗体
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
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71 results
EGLN1
适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our EGLN1 抗体
: "Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5426, (2019) (PubMed).: "Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. ..." in: Nature communications, Vol. 10, Issue 1, pp. 903, (2019) (PubMed).
: "Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages." in: Cell reports, Vol. 27, Issue 13, pp. 3873-3886.e7, (2019) (PubMed).
: "A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension." in: Nature communications, Vol. 10, Issue 1, pp. 2130, (2019) (PubMed).
: "Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. ..." in: The Journal of clinical investigation, Vol. 130, pp. 3640-3656, (2019) (PubMed).
: "The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia." in: Cell metabolism, Vol. 27, Issue 4, pp. 898-913.e7, (2018) (PubMed).
: "Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat." in: Anatolian journal of cardiology, Vol. 19, Issue 4, pp. 259-266, (2018) (PubMed).
: "Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen." in: Nature communications, Vol. 9, Issue 1, pp. 4545, (2018) (PubMed).
: "The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels." in: eLife, Vol. 6, (2017) (PubMed).
: "Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice." in: Journal of cellular and molecular medicine, (2017) (PubMed).
Aliases for EGLN1 抗体
egl nine homolog 1 (C. elegans) (EGLN1) 抗体egl-9 family hypoxia inducible factor 1 (EGLN1) 抗体
egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S) 抗体
egl-9 family hypoxia-inducible factor 1b (egln1b) 抗体
egl-9 family hypoxia-inducible factor 1 (Egln1) 抗体
AI503754 抗体
C1orf12 抗体
ECYT3 抗体
EGLN1 抗体
egln2 抗体
Hif-p4h-2 抗体
HIF-PH2 抗体
HIFPH2 抗体
HPH-2 抗体
HPH2 抗体
ORF13 抗体
PHD-2 抗体
phd2 抗体
Phd2 抗体
PHD2 抗体
SM-20 抗体
SM20 抗体
zgc:92314 抗体
ZMYND6 抗体
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