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DYRK1A 抗体

(Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008].

72 results

DYRK1A 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693108
 
DYRK1A 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782363
 
DYRK1A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB12637 unconjugated
产品编号 ABIN391799
 
DYRK1A 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783434
 
DYRK1A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359711
 
DYRK1A 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN264978
 
DYRK1A 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5558265
 
DYRK1A 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal Biotin
产品编号 ABIN5558266
 
DYRK1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7616271
 
DYRK1A 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal FITC
产品编号 ABIN5558267
 
DYRK1A 适用: 人 WB, ELISA, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2256614
 
DYRK1A 适用: 人 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6332690
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Rabbit
    • Monkey
    • Cow
    • Guinea Pig
    • Horse
    • Pig
    • Bat
    • Chicken
    • Dog
    • Xenopus laevis
    • Zebrafish (Danio rerio)
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 7D10
    • RB12637
    • RB13055
    • RB40563
  • 抗原表位
    • AA 81-170
    • N-Term
    • AA 107-136
    • AA 718-745
    • AA 389-418
    • C-Term
    • AA 674-763
    • AA 16-300
    • AA 713-763
    • AA 107-156
    • AA 21-70
    • AA 22-71
    • AA 25-50
    • AA 38-269
    • AA 486-763
    • AA 624-763
    • Gln39
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • APC
    • PE
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG2b
    • IgG2b kappa
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Abcepta
    • Acris
    • FabGennix
    • NSJ Bioreagents
    • Abbexa
    • Assay Biotechnology Company, Inc.
    • Aviva Systems Biology
    • Biomatik
    • Boster Bio
    • Cohesion Biosciences
    • USBio

Latest Publications for our DYRK1A 抗体

Widowati, Bamberg-Lemper, Becker: "Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A." in: BMC research notes, Vol. 11, Issue 1, pp. 297, (2018) (PubMed).

Widowati, Ernst, Hausmann, Müller-Newen, Becker: "Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism." in: Biology open, Vol. 7, Issue 4, (2018) (PubMed).

Rabaneda, Geribaldi-Doldán, Murillo-Carretero, Carrasco, Martínez-Salas, Verástegui, Castro: "Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation." in: Biochimica et biophysica acta, Vol. 1863, Issue 12, pp. 3015-3026, (2016) (PubMed).

Souchet, Latour, Gu, Daubigney, Paul, Delabar, Janel: "Molecular rescue of DYRK1A overexpression in cystathionine beta synthase-deficient mouse brain by enriched environment combined with voluntary exercise." in: Journal of molecular neuroscience : MN, Vol. 55, Issue 2, pp. 318-23, (2015) (PubMed).

Thompson, Bhansali, Diebold, Cook, Stolzenburg, Casagrande, Besson, Leblond, Désiré, Malinge, Crispino: "DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3." in: The Journal of experimental medicine, Vol. 212, Issue 6, pp. 953-70, (2015) (PubMed).

Najas, Arranz, Lochhead, Ashford, Oxley, Delabar, Cook, Barallobre, Arbonés: "DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome." in: EBioMedicine, Vol. 2, Issue 2, pp. 120-34, (2015) (PubMed).

Blazek, Abeysekera, Li, Roper: "Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a." in: Human molecular genetics, Vol. 24, Issue 20, pp. 5687-96, (2015) (PubMed).

Stringer, Abeysekera, Dria, Roper, Goodlett: "Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model." in: Pharmacology, biochemistry, and behavior, Vol. 138, pp. 70-9, (2015) (PubMed).

Fant, Durieu, Chicanne, Payrastre, Sbrissa, Shisheva, Limanton, Carreaux, Bazureau, Meijer: "cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease." in: Molecular pharmacology, Vol. 85, Issue 3, pp. 441-50, (2014) (PubMed).

Hibaoui, Grad, Letourneau, Sailani, Dahoun, Santoni, Gimelli, Guipponi, Pelte, Béna, Antonarakis, Feki: "Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21." in: EMBO molecular medicine, Vol. 6, Issue 2, pp. 259-77, (2014) (PubMed).

Aliases for DYRK1A 抗体

dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) 抗体
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (dyrk1a) 抗体
dual specificity tyrosine phosphorylation regulated kinase 1A (dyrk1a) 抗体
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a) 抗体
dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a) 抗体
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog (dyrk1a.S) 抗体
2310043O08Rik 抗体
D16Ertd272e 抗体
D16Ertd493e 抗体
dyrk 抗体
DYRK 抗体
Dyrk 抗体
dyrk1 抗体
DYRK1 抗体
DYRK1A 抗体
ENSMUSG00000074897 抗体
Gm10783 抗体
hp86 抗体
HP86 抗体
mmb 抗体
mnb 抗体
MNB 抗体
mnbh 抗体
MNBH 抗体
Mnbh 抗体
Mp86 抗体
MRD7 抗体
PSK47 抗体
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