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DUOXA1 抗体

(Dual Oxidase Maturation Factor 1 (DUOXA1))
Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013].

11 results

DUOXA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN530004
 
DUOXA1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150692
 
DUOXA1 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6747594
 
DUOXA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926689
 
DUOXA1 适用: 人 ELISA, WB, ICC, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387935
 
DUOXA1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7150695
 
DUOXA1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7150694
 
DUOXA1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7150693
 
DUOXA1 适用: 人, 犬, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788717
 
DUOXA1 适用: 人 ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN6086350
 
DUOXA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN2256086
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (IF)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 适用
    • Human
    • Dog
    • Pig
    • Cow
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
  • 抗原表位
    • AA 73-183
    • C-Term
    • AA 1-298
    • AA 1-299
    • AA 101-200
    • AA 297-346
  • 标记
    • 非结合性
    • FITC
    • Biotin
    • HRP
  • 抗体亚型
    • IgG
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Abbexa
    • Aviva Systems Biology
    • USBio

Latest Publications for our DUOXA1 抗体

Little, Sham, Hristova, Danyal, Heppner, Bauer, Sipsey, Habibovic, van der Vliet: "DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties." in: Oncogenesis, Vol. 5, Issue 10, pp. e261, (2016) (PubMed).

Aliases for DUOXA1 抗体

dual oxidase maturation factor 2 (DUOXA2) 抗体
dual oxidase maturation factor 1 (DUOXA1) 抗体
dual oxidase maturation factor 1 (LOC100405759) 抗体
dual oxidase maturation factor 1 (Duoxa1) 抗体
BC019755 抗体
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NIP 抗体
Nip 抗体
Nip1 抗体
NUMBIP 抗体
RGD1306601 抗体
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