MBD4 抗体
(Methyl-CpG Binding Domain Protein 4 (MBD4))
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013].
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Latest Publications for our MBD4 抗体
: "Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis." in: British journal of cancer, Vol. 110, Issue 3, pp. 668-78, (2014) (PubMed).: "Polymorphisms in the base excision repair pathway and graft-versus-host disease." in: Leukemia, Vol. 24, Issue 8, pp. 1470-5, (2010) (PubMed).
: "Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations." in: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Vol. 16, Issue 8, pp. 1084-9, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." in: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).
: "Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples." in: Human molecular genetics, Vol. 14, Issue 6, pp. 785-97, (2005) (PubMed).
Aliases for MBD4 抗体
methyl-CpG binding domain 4, DNA glycosylase (MBD4) 抗体methyl-CpG binding domain protein 4 (Mbd4) 抗体
methyl-CpG binding domain 4 DNA glycosylase (Mbd4) 抗体
MED1 抗体
Med1 抗体
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