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DDX58 产品

(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Categories

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008].

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Featured DDX58 Categories

DDX58 抗体

High quality antibodies with extensive validation data.

DDX58 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DDX58 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DDX58 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7433744
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7440305
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN6391376
Quantity 100 μg
Datasheet Datasheet

Recommended DDX58 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1770972
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774644
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2851498
Quantity 96 tests
Datasheet Datasheet

Recommended DDX58 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351378
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135827
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3078828
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DDX58 Products

Kell, Hemann, Turnbull, Gale: "RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit Hantaan orthohantavirus replication." in: PLoS pathogens, Vol. 16, Issue 4, pp. e1008483, (2020) (PubMed).

Moriyama, Koshiba, Ichinohe: "Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses." in: Nature communications, Vol. 10, Issue 1, pp. 4624, (2020) (PubMed).

Soonthornvacharin, Rodriguez-Frandsen, Zhou, Galvez, Huffmaster, Tripathi, Balasubramaniam, Inoue, de Castro, Moulton, Stein, Sánchez-Aparicio, De Jesus, Nguyen, König, Krogan, García-Sastre, Yoh et al.: "Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. ..." in: Nature microbiology, Vol. 2, pp. 17022, (2018) (PubMed).

Ranoa, Parekh, Pitroda, Huang, Darga, Wong, Huang, Andrade, Staley, Satoh, Akira, Weichselbaum, Khodarev: "Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs." in: Oncotarget, Vol. 7, Issue 18, pp. 26496-515, (2018) (PubMed).

Zhu, Ye, Ashraf, Li, Chen, Song, Cao: "Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection." in: Scientific reports, Vol. 6, pp. 22581, (2017) (PubMed).

Korolowicz, Iyer, Czerwinski, Suresh, Yang, Padmanabhan, Sheri, Pandey, Skell, Marquis, Kallakury, Tucker, Menne: "Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161313, (2017) (PubMed).

Harden, Munger: "Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles." in: Virology, Vol. 508, pp. 63-69, (2017) (PubMed).

Zhu, Duan, Wang, Cao, Liu: "TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages." in: Experimental cell research, Vol. 345, Issue 1, pp. 70-81, (2016) (PubMed).

Pei, Deng, Ye, Wang, Gou, Liu, Zhao, Liao, Yi, Chen: "Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells." in: Autophagy, Vol. 12, Issue 10, pp. 1738-1758, (2016) (PubMed).

Cheng, Liao, Zhou, Peng, Chen, Yuan: "Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop." in: Scientific reports, Vol. 6, pp. 20158, (2016) (PubMed).

Synonyms and alternative names related to DDX58

DExD/H-box helicase 58 (DDX58), DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58), DEXD/H-box helicase 58 (Ddx58), DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58), 6430573D20Rik, C330021E21, RHIV-1, RIG-1, RIG-I, RIGI, RLR-1

Protein level used designations for DDX58

  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
  • probable ATP-dependent RNA helicase DDX58
  • putative ATP-dependent RNA helicase DDX58
  • retinoic acid-inducible protein I
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
  • probable ATP-dependent RNA helicase DDX58-like
  • DEAD box protein 58
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
  • RIG-1
  • RIG-I-like receptor 1
  • RNA helicase RIG-I
  • retinoic acid inducible gene I
  • retinoic acid-inducible gene 1 protein
  • retinoic acid-inducible gene I protein
  • DEAD-box protein 58
  • DEAD/H box polypeptide RIG-I
  • retinoic acid-inducible gene-I
  • RNA helicase induced by virus
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