DDX3X 产品
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
Categories
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010].
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Featured DDX3X Categories
DDX3X 抗体
High quality antibodies with extensive validation data.
DDX3X ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DDX3X 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DDX3X 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN6139494
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (10)
Cat. No.
ABIN5542508
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7261584
Quantity
200 μL
Datasheet
Datasheet
Recommended DDX3X ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966272
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381081
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6215946
Quantity
96 tests
Datasheet
Datasheet
Recommended DDX3X 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351345
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2719282
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7576527
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DDX3X Products
: "The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma. ..." in: Cell reports, Vol. 27, Issue 12, pp. 3573-3586.e7, (2019) (PubMed).: "Regulation of p21 expression for anti-apoptotic activity of DDX3 against sanguinarine-induced cell death on intrinsic pathway." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 65, pp. 153096, (2019) (PubMed).
: "Proteome analysis of Duck Tembusu virus (DTMUV)-infected BHK-21 cells." in: Proteomics, Vol. 17, Issue 12, (2017) (PubMed).
: "The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas." in: Disease markers, Vol. 2015, pp. 379568, (2015) (PubMed).
"Correction: reduced p21WAF1/CIP1 via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 4, pp. 935, (2015) (PubMed).
: "A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1." in: Retrovirology, Vol. 11, pp. 121, (2015) (PubMed).
: "DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer." in: Oncogene, Vol. 33, Issue 12, pp. 1515-26, (2014) (PubMed).
: "Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers." in: Cancer discovery, Vol. 3, Issue 9, pp. 1044-57, (2013) (PubMed).
: "The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 985-96, (2012) (PubMed).
: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).
Synonyms and alternative names related to DDX3X
DEAD-box helicase 3, X-linked (DDX3X), DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x), DEAD-box helicase 3, X-linked (Ddx3x), DEAD-box helicase 3, X-linked L homeolog (ddx3x.L), DEAD-box helicase 3, X-linked (ddx3x), An3, D1Pas1-rs2, DBX, DDX3, Ddx3, DDX3X, DDX14, Fin14, HLP2, pl10Protein level used designations for DDX3X
- ATP-dependent RNA helicase DDX3X
- CAP-Rf
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
- DEAD box protein 3, X-chromosomal
- DEAD box, X isoform
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3
- DEAD/H box-3
- helicase like protein 2
- helicase-like protein 2
- D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3
- D1Pas1-related sequence 2
- DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3
- DEAD box RNA helicase DEAD3
- DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2)
- embryonic RNA helicase
- fibroblast growth factor inducible 14
- mDEAD3
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
- ATP-dependent RNA helicase DDX3X-like
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