DCTPP1 抗体
(DCTP Pyrophosphatase 1 (DCTPP1))
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non- canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases (By similarity).
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Latest Publications for our DCTPP1 抗体
: "Comparative proteomics analysis of gastric cancer stem cells." in: PLoS ONE, Vol. 9, Issue 11, pp. e110736, (2014) (PubMed).: "dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas." in: European journal of histochemistry : EJH, Vol. 57, Issue 3, pp. e29, (2014) (PubMed).
: "Triptolide directly inhibits dCTP pyrophosphatase." in: Chembiochem : a European journal of chemical biology, Vol. 12, Issue 11, pp. 1767-73, (2011) (PubMed).
Aliases for DCTPP1 抗体
dCTP pyrophosphatase 1 (DCTPP1) 抗体dCTP pyrophosphatase 1 (Dctpp1) 抗体
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