(Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008].
Wu, Martin, Javitt, Chiang: "Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1." in: Journal of lipid research, Vol. 40, Issue 12, pp. 2195-203, (2000) (PubMed).
Aliases for CYP7B1 抗体
cytochrome P450 family 7 subfamily B member 1 (CYP7B1) 抗体 cytochrome P450 family 7 subfamily B member 1 (cyp7b1) 抗体 cytochrome P450, family 7, subfamily B, polypeptide 1 (CYP7B1) 抗体 cytochrome P450, family 7, subfamily b, polypeptide 1 (Cyp7b1) 抗体 cytochrome P450 family 7 subfamily B member 1 (Cyp7b1) 抗体 AW261589 抗体 CBAS3 抗体 CP7B 抗体 CYP7B1 抗体 D3Ertd552e 抗体 hct-1 抗体 SPG5A 抗体