CYP46A1 抗体
(Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].
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Latest Publications for our CYP46A1 抗体
: "Cytochrome P450s and cholesterol homeostasis." in: Pharmacology & therapeutics, Vol. 112, Issue 3, pp. 761-73, (2006) (PubMed).: "Differential expression of cholesterol hydroxylases in Alzheimer's disease." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34674-81, (2004) (PubMed).
: "Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain." in: Biochemistry, Vol. 42, Issue 48, pp. 14284-92, (2003) (PubMed).
Aliases for CYP46A1 抗体
cytochrome P450 family 46 subfamily A member 1 (CYP46A1) 抗体cytochrome P450 family 46 subfamily A member 1 L homeolog (cyp46a1.L) 抗体
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 (cyp46a1.1) 抗体
cytochrome P450, family 46 (cyp46a1) 抗体
cytochrome P450 46A1 (PTRG_08343) 抗体
cytochrome P450 46A1 (PTRG_09667) 抗体
cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1) 抗体
cholesterol 24-hydroxylase (Sgly_1093) 抗体
cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1) 抗体
CP46 抗体
CYP46 抗体
Cyp46 抗体
CYP46A1 抗体
MGC147389 抗体
zgc:109896 抗体
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