CYP2A6 抗体
(Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3\; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008].
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55 results
CYP2A6
适用: 人
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
宿主: 兔
Polyclonal
unconjugated
CYP2A6
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
CYP2A6
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
Latest Publications for our CYP2A6 抗体
: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).: "Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes." in: Pharmacogenomics, Vol. 12, Issue 4, pp. 481-92, (2011) (PubMed).
: "Inhibitory effects of neurotransmitters and steroids on human CYP2A6." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 35, Issue 4, pp. 508-14, (2007) (PubMed).
: "The role of CYP2A6 in the emergence of nicotine dependence in adolescents." in: Pediatrics, Vol. 119, Issue 1, pp. e264-74, (2007) (PubMed).
: "Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence." in: Pharmacogenetics and genomics, Vol. 15, Issue 2, pp. 115-25, (2005) (PubMed).
: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
: "The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes." in: Biochemistry, Vol. 29, Issue 5, pp. 1322-9, (1990) (PubMed).
: "Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity." in: Nucleic acids research, Vol. 17, Issue 8, pp. 2907-17, (1989) (PubMed).
: "cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)." in: Nucleic acids research, Vol. 17, Issue 12, pp. 4888, (1989) (PubMed).
Aliases for CYP2A6 抗体
cytochrome P450 family 2 subfamily A member 6 (CYP2A6) 抗体cytochrome P450 2A6 (CYP2A6) 抗体
cytochrome P450 family 2 subfamily A member 6 L homeolog (cyp2a6.L) 抗体
CPA6 抗体
CYP2A 抗体
CYP2A3 抗体
cyp2a6 抗体
CYPIIA6 抗体
P450C2A 抗体
P450PB 抗体
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