(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity).
Vlach, Quesnot, Dubois-Pot-Schneider, Ribault, Verres, Petitjean, Rauch, Morel, Robin, Corlu, Loyer: "Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity." in: Sensors (Basel, Switzerland), Vol. 19, Issue 10, (2019) (PubMed).
Volková, Forstová-Krízová, Skálová, Trejtnar: "Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 in intestinal HCT-8 cells." in: Phytotherapy research : PTR, Vol. 27, Issue 12, pp. 1889-93, (2014) (PubMed).
Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Aliases for CYP1A1/2 抗体
cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2) 抗体 CP12 抗体 Cyp1a1 抗体 P450-3 抗体