CYB5R3 抗体
(Cytochrome B5 Reductase 3 (CYB5R3))
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010].
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
ABIN5539504
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our CYB5R3 抗体
: "Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase." in: Mutation research, Vol. 852, pp. 503162, (2020) (PubMed).: "Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine." in: Toxicology and applied pharmacology, Vol. 366, pp. 64-74, (2019) (PubMed).
: "Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice." in: Archives of toxicology, Vol. 92, Issue 4, pp. 1625-1638, (2019) (PubMed).
: "The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice." in: PloS one, Vol. 9, Issue 8, pp. e105371, (2014) (PubMed).
: "RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1." in: Journal of cell science, Vol. 118, Issue Pt 12, pp. 2661-70, (2005) (PubMed).
Aliases for CYB5R3 抗体
cytochrome b5 reductase 3 (CYB5R3) 抗体cytochrome b5 reductase 3 (Cyb5r3) 抗体
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