Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Shimaoka, Kume, Minami, Hayashida, Kataoka, Kita, Yonehara: "Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 40663-6, (2001) (PubMed).