CTIF/KIAA0427 蛋白
(CBP80/20-Dependent Translation Initiation Factor (CTIF))
CTIF is a component of the CBP80 (NCBP1\; MIM 600469)/CBP20 (NCBP2\; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009].
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custom-made
CTIF
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
CTIF
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for CTIF/KIAA0427 蛋白
cap binding complex dependent translation initiation factor (CTIF) 蛋白CBP80/20-dependent translation initiation factor (CTIF) 蛋白
CBP80/20-dependent translation initiation factor (ctif) 蛋白
CBP80/20-dependent translation initiation factor (Ctif) 蛋白
similar to Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (LOC679129) 蛋白
cap binding complex dependent translation initiation factor (Ctif) 蛋白
Gm672 蛋白
gm672 蛋白
KIAA0427 蛋白
kiaa0427 蛋白
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