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CTCF 蛋白

(CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

11 results :

custom-made CTCF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7563903
 
custom-made CTCF 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7553593
 
CTCF 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Pubmed 3 references
产品编号 ABIN7536632
 
CTCF 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Pubmed 1 reference
产品编号 ABIN1350630
 
CTCF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
产品编号 ABIN7122187
 
CTCF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319104
 
CTCF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant ELISA, WB, SDS
产品编号 ABIN7576402
 
CTCF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691993
 
custom-made CTCF 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3135365
 
custom-made CTCF 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3091995
 
CTCF 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7591231
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • 适用
    • Human
    • Mouse
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • 抗原表位
    • AA 1-727
    • AA 1-154
    • AA 1-736
    • AA 1-100
    • AA 1-737
  • 标记
    • His tag
    • GST tag
    • Strep Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO

Latest Publications for our CTCF 蛋白

Al-Mahdawi, Sandi, Mouro Pinto, Pook: "Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus." in: PLoS ONE, Vol. 8, Issue 9, pp. e74956, (2013) (PubMed).

Shukla, Kavak, Gregory, Imashimizu, Shutinoski, Kashlev, Oberdoerffer, Sandberg, Oberdoerffer: "CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing." in: Nature, Vol. 479, Issue 7371, pp. 74-9, (2011) (PubMed).

Li, Hu, Qiu, Ling, Chen, Wang, Hou, Vu, Hoffman: "CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop." in: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6473-82, (2008) (PubMed).

Aliases for CTCF 蛋白

CCCTC-binding factor (CTCF) 蛋白
CCCTC-binding factor (zinc finger protein) (ctcf) 蛋白
CCCTC-binding factor (ctcf) 蛋白
CCCTC-binding factor (Ctcf) 蛋白
AW108038 蛋白
CTCF 蛋白
im:7152666 蛋白
xctcf 蛋白
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