This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
Rashid, Runci, Polletta, Carnevale, Morgante, Foglio, Arcangeli, Sansone, Russo, Tafani: "Muscle LIM protein/CSRP3: a mechanosensor with a role in autophagy." in: Cell death discovery, Vol. 1, pp. 15014, (2016) (PubMed).
Roberts, Childs, Brown, Davis, Booth: "Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 112, Issue 8, pp. 1291-9, (2012) (PubMed).
Zheng, Wen, Han: "hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling." in: The FEBS journal, Vol. 275, Issue 7, pp. 1568-78, (2008) (PubMed).
Aliases for CSRP3 抗体
cysteine and glycine rich protein 3 (CSRP3) 抗体 cysteine and glycine-rich protein 3 (Csrp3) 抗体 cysteine and glycine rich protein 3 (Csrp3) 抗体 cysteine and glycine rich protein 3 (csrp3) 抗体 cysteine and glycine-rich protein 3 (cardiac LIM protein) (csrp3) 抗体 cysteine and glycine rich protein 3 L homeolog (csrp3.L) 抗体 CLP 抗体 CMD1M 抗体 CMH12 抗体 CRP3 抗体 csrp3 抗体 CSRP3 抗体 csrp3-a 抗体 LMO4 抗体 MLP 抗体 MMLP 抗体 zgc:103468 抗体