Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2008].
custom-made
CSNK2A1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
CSNK2A1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Latest Publications for our CSNK2A1/CK II alpha 蛋白
Peng, Wang, Hu, Zhao, Hou, Zhao, Wang, Liao, Xu: "Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage." in: Nucleic acids research, Vol. 43, Issue 12, pp. 5936-47, (2015) (PubMed).
Wang, Schachner: "The intracellular domain of L1CAM binds to casein kinase 2? and is neuroprotective via inhibition of the tumor suppressors PTEN and p53." in: Journal of neurochemistry, Vol. 133, Issue 6, pp. 828-43, (2015) (PubMed).