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CSK 蛋白

(C-Src tyrosine Kinase (CSK))
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).

13 results :

CSK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Pubmed 1 reference
产品编号 ABIN1350517
 
CSK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95% by SDS-PAGE SDS
产品编号 ABIN5853916
 
CSK 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
产品编号 ABIN7320001
 
CSK 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317088
 
CSK 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
产品编号 ABIN7320121
 
CSK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
产品编号 ABIN2712578
 
CSK 宿主: 人 宿主: Insect Cells Recombinant 70 % - 90 % Func Active
产品编号 ABIN5508887
 
CSK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7418323
 
CSK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN2128725
 
CSK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712579
 
CSK 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7587816
 
CSK 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583985
 
CSK 宿主: 小鸡 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1459024
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Mouse
    • Chicken
    • Cow
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Baculovirus infected Insect Cells
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Insect Cells
    • Wheat germ
  • 抗原表位
    • AA 1-450
    • AA 2-450
    • AA 243-438
    • Transcript Variant 1
    • Transcript Variant 2
  • 标记
    • His tag
    • 非结合性
    • GST tag
    • Myc-DYKDDDDK Tag
    • GST tag,His tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
    • Frozen
  • 生物活性
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene

Latest Publications for our CSK 蛋白

Jo, Park, Lee, Ahn, Kim, Park, Choi: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).

Aliases for CSK 蛋白

C-terminal Src kinase (CSK) 蛋白
c-src tyrosine kinase (Csk) 蛋白
C-terminal Src kinase (Csk) 蛋白
c-src tyrosine kinase (CSK) 蛋白
CSK, non-receptor tyrosine kinase (CSK) 蛋白
AW212630 蛋白
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