The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010].
Ko, Chandra, Ouyang, Kwon, Karande, Han: "Nanofluidic device for continuous multiparameter quality assurance of biologics." in: Nature nanotechnology, Vol. 12, Issue 8, pp. 804-812, (2019) (PubMed).
Tsuchida, Yamazaki, Akashi: "Characterization of stress-exposed granulocyte colony stimulating factor using ELISA and hydrogen/deuterium exchange mass spectrometry." in: Journal of the American Society for Mass Spectrometry, Vol. 25, Issue 10, pp. 1747-54, (2014) (PubMed).