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Crystallin, alpha B 蛋白

(Crystallin, alpha B (CRYAB))
Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].

26 results :

custom-made CRYAB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7562991
 
custom-made CRYAB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7546772
 
CRYAB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1350424
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN934884
 
CRYAB 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN934981
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319198
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7576363
 
CRYAB 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % SDS, WB, Imm, PC
产品编号 ABIN7396997
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7396994
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90% by SDS-PAGE SDS
产品编号 ABIN7596350
 
custom-made CRYAB 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3133386
 
CRYAB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5709329
 
CRYAB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714621
 
CRYAB 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583958
 
CRYAB 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583957
 
CRYAB 宿主: Blackbird 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1655820
 
CRYAB 宿主: Columba livia 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1655882
 
CRYAB 宿主: Trachemys scripta 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1640277
 
CRYAB 宿主: Bullfrog 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1640274
 
CRYAB 宿主: 鸭 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1609758
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Blackbird
    • Bullfrog
    • Chicken
    • Columba livia
    • Cow
    • Dogfish (Squalus)
    • Duck
    • Golden Syrian Hamster
    • Orang-Utan
    • Rabbit
    • Rat
    • Sheep
    • Trachemys scripta
  • 图像
  • Carrier free only
  • 抗体来源
    • Yeast
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • 抗原表位
    • AA 1-175
    • AA 1-52
    • AA 1-174
    • AA 1-173
    • AA 1-177
    • full length
  • 标记
    • His tag
    • 非结合性
    • GST tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • CUSABIO
    • antibodies-online
    • OriGene
    • Signalway

Latest Publications for our Crystallin, alpha B 蛋白

Anders, Liu, Mann, Teister, Lauzi, Thanos, Grus, Pfeiffer, Prokosch: "The Small Heat Shock Protein α-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model." in: International journal of molecular sciences, Vol. 18, Issue 11, (2018) (PubMed).

Aliases for Crystallin, alpha B 蛋白

crystallin alpha B (CRYAB) 蛋白
crystallin, alpha B (Cryab) 蛋白
hypothetical protein (ZK1128.7) 蛋白
crystallin alpha B (Cryab) 蛋白
crystallin, alpha B, a (cryaba) 蛋白
crystallin, alpha B, b (cryabb) 蛋白
AACRYA 蛋白
CMD1II 蛋白
Crya-2 蛋白
CRYA2 蛋白
Crya2 蛋白
CRYAB 蛋白
cryab 蛋白
cryab2 蛋白
CTPP2 蛋白
CTRCT16 蛋白
HSPB5 蛋白
HspB5 蛋白
MFM2 蛋白
wu:fe37f08 蛋白
zgc:91937 蛋白
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