The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Labasque, Hivert, Nogales-Gadea, Querol, Illa, Faivre-Sarrailh: "Specific contactin N-glycans are implicated in neurofascin binding and autoimmune targeting in peripheral neuropathies." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7907-18, (2014) (PubMed).