COPRS 蛋白
(Coordinator of PRMT5, Differentiation Stimulator (COPRS))
Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity).
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COPRS
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Aliases for COPRS 蛋白
coordinator of PRMT5 and differentiation stimulator (COPRS) 蛋白coordinator of PRMT5, differentiation stimulator (Coprs) 蛋白
1700029I03Rik 蛋白
2410022L05Rik 蛋白
AA409325 蛋白
AI256813 蛋白
C17orf79 蛋白
C19H17orf79 蛋白
C85432 蛋白
COPR5 蛋白
Copr5 蛋白
HSA272196 蛋白
TTP1 蛋白
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