Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity).
Latest Publications for our Cold Inducible RNA Binding Protein 蛋白
Qiang, Yang, Wu, Zhou, Jacob, Dong, Kuncewitch, Ji, Yang, Wang, Fujita, Nicastro, Coppa, Tracey, Wang: "Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis." in: Nature medicine, Vol. 19, Issue 11, pp. 1489-95, (2013) (PubMed).
Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: "Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 7, pp. 1992-2000, (2012) (PubMed).
Aliases for Cold Inducible RNA Binding Protein 蛋白
cold inducible RNA binding protein (CIRBP) 蛋白 cold-inducible RNA-binding protein (EDI_107320) 蛋白 cold inducible RNA binding protein (Cirbp) 蛋白 cold inducible RNA binding protein S homeolog (cirbp.S) 蛋白 cold inducible RNA binding protein L homeolog (cirbp.L) 蛋白 cold inducible RNA binding protein (cirbp) 蛋白 cold inducible RNA binding protein b (cirbpb) 蛋白 A18 hnRNP 蛋白 APBP-1 蛋白 cirbp 蛋白 CIRBP 蛋白 cirbp-a 蛋白 cirbp-b 蛋白 cirbp2 蛋白 CIRP 蛋白 Cirp 蛋白 cirp 蛋白 cirp-1 蛋白 cirp1 蛋白 cirp2 蛋白 R74941 蛋白 Xcirp 蛋白 XCIRP 蛋白 XCIRP-1 蛋白 xcirp2 蛋白 zgc:136559 蛋白