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Catechol-O-Methyltransferase 抗体

(Catechol-O-Methyltransferase (COMT))
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].

97 results

Verified COMT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185682
 
KO Validated COMT 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN2854980
 
Verified COMT 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185328
 
COMT 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043815
 
COMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4-1A1 unconjugated
产品编号 ABIN560435
 
COMT 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7436675
 
COMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN514524
 
COMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN514522
 
COMT 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN768669
 
COMT 适用: 人, 大鼠, 小鼠, 猴, Cow, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN768668
 
COMT 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8E1 unconjugated Recombinant Antibody
产品编号 ABIN7127433
 
COMT 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN6258028
 
COMT 适用: 人 WB 宿主: 小鼠 Monoclonal 630CT1-7-1 unconjugated
Pubmed 5 references
产品编号 ABIN1882224
 
COMT 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781821
 
COMT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN560434
 
Verified COMT 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin
产品编号 ABIN6391373
 
COMT 适用: 人, 猴, 犬, Cow, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6741819
 
COMT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138867
 
COMT 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1858471
 
COMT 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1858470
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • ELISA
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Flow Cytometry (FACS)
    • Immunochromatography (IC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 适用
    • Human
    • Rat
    • Mouse
    • Monkey
    • Cow
    • Pig
    • Dog
    • Horse
    • Rabbit
    • Bat
    • Guinea Pig
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • C4
    • 8E1
    • C1
    • C2
    • C3
    • C5
    • C7
    • 15C10
    • 1G4-1A1
    • 20C06
    • 630CT1-7-1
  • 抗原表位
    • AA 121-220
    • AA 52-271
    • AA 63-264
    • Internal Region
    • AA 1-221
    • AA 31-264
    • AA 63-265
    • N-Term
    • AA 1-182
    • AA 221-271
    • AA 111-156
    • AA 143-192
    • AA 20-265
    • AA 30-110
    • AA 37-65
    • AA 42-221
    • AA 52-101
    • AA 61-110
    • AA 94-108
    • C-Term
    • Center
    • Middle Region
  • 标记
    • 非结合性
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • FITC
    • HRP
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • IgG1 kappa
    • IgG2b
    • IgG1
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
    • KD Validated
    • KO Validated
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • Abbexa
    • Boster Bio
    • Cloud-Clone
    • USBio
    • Angio-Proteomie
    • Assay Biotechnology Company, Inc.
    • Aviva Systems Biology
    • Cohesion Biosciences
    • Wuhan Fine biotech

Latest Publications for our Catechol-O-Methyltransferase 抗体

Bai, Tang, Zou, Meng, Tu, Xia, Cheng, Zhang, Yang, Mu, Wang, Qin, Lv, Cao, Qin, Jiang, Chen: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).

Ikeda, Iijima, Shinoda, Iwamoto, Takeda: "Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase." in: Molecules (Basel, Switzerland), Vol. 22, Issue 8, (2018) (PubMed).

Yang, Yao, Zhou, Yin, Zhang, Harris: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." in: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, (2012) (PubMed).

Hevir, Sinkovec, Rižner: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." in: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).

Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Stroth, Reinhardt, Thöne, Hille, Schneider, Härtel, Weidemann, Bös, Spitzer: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." in: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).

Lim, Kim, Kim, Park, Han, Han, Lee, Yang, Ryu: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).

Demetrovics, Varga, Szekely, Vereczkei, Csorba, Balazs, Hoffman, Sasvari-Szekely, Barta: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." in: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).

Bodenmann, Landolt: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." in: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).

Yao, Harris, Zhang: "Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway." in: Hypertension (Dallas, Tex. : 1979), Vol. 54, Issue 5, pp. 1077-83, (2009) (PubMed).

Aliases for Catechol-O-Methyltransferase 抗体

catechol-O-methyltransferase (COMT) 抗体
catechol-O-methyltransferase (Comt) 抗体
microRNA 4761 (MIR4761) 抗体
catechol-O-methyltransferase (comt) 抗体
catechol-O-methyltransferase (comt.2) 抗体
catechol-O-methyltransferase S homeolog (comt.S) 抗体
methyltransferase (Rv1703c) 抗体
catechol-o-methyltransferase (Mb1729c) 抗体
catechol-O-methyltransferase a (comta) 抗体
catechol-O-methyltransferase b (comtb) 抗体
catechol O-methyltransferase (LOC100354142) 抗体
COMT 抗体
comt 抗体
Comt1 抗体
D16Wsu103e 抗体
D330014B15Rik 抗体
mb-comt 抗体
MGC154444 抗体
s-comt 抗体
si:dkey-13a21.15 抗体
zgc:114157 抗体
zgc:162236 抗体
zK13A21.15 抗体
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