The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Sultana, Nakaya, Dong, Abu-Asab, Qian, Tomarev: "Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice." in: Experimental neurology, Vol. 261, pp. 802-11, (2014) (PubMed).
Aliases for CNIH2 抗体
cornichon family AMPA receptor auxiliary protein 2 (Cnih2) 抗体 cornichon family AMPA receptor auxiliary protein 2 (CNIH2) 抗体 cornichon family AMPA receptor auxiliary protein 2 (cnih2) 抗体 cornichon family AMPA receptor auxiliary protein 2 S homeolog (cnih2.S) 抗体 CNIH-2 抗体 cnih-2 抗体 cnih2 抗体 Cnih3 抗体 Cnil 抗体 CNIL 抗体 cnil 抗体 RGD1304930 抗体 zgc:101874 抗体