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CLOCK 产品

(Clock Homolog (Mouse) (CLOCK))
This gene product regulates circadian rhythm and metabolism. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and a DNA binding histone acetyltransferase. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].

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Featured CLOCK Categories

CLOCK 抗体

High quality antibodies with extensive validation data.

CLOCK ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CLOCK 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLOCK 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6260894
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7266414
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7147793
Quantity 100 μg
Datasheet Datasheet

Recommended CLOCK ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954841
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954842
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648169
Quantity 96 tests
Datasheet Datasheet

Recommended CLOCK 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349727
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349725
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091603
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CLOCK Products

Menet, Rodriguez, Abruzzi, Rosbash: "Nascent-Seq reveals novel features of mouse circadian transcriptional regulation." in: eLife, Vol. 1, pp. e00011, (2012) (PubMed).

Kalamvoki, Roizman: "Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 41, pp. 17721-6, (2010) (PubMed).

Xu, Krager, Liao, Tischkau: "Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 1, pp. 98-108, (2010) (PubMed).

Kuo, Chen, Yeh, Hou, Chang, Hsu, Chang: "Disturbance of circadian gene expression in breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 4, pp. 467-74, (2009) (PubMed).

Marino, Holt, Chen, Davis: "Shift work, hCLOCK T3111C polymorphism, and endometriosis risk." in: Epidemiology (Cambridge, Mass.), Vol. 19, Issue 3, pp. 477-84, (2008) (PubMed).

Nakashima, Kawamoto, Honda, Ueshima, Noshiro, Iwata, Fujimoto, Kubo, Honma, Yorioka, Kohno, Kato: "DEC1 modulates the circadian phase of clock gene expression." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 4080-92, (2008) (PubMed).

Sookoian, Gemma, Gianotti, Burgueño, Castaño, Pirola: "Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity." in: The American journal of clinical nutrition, Vol. 87, Issue 6, pp. 1606-15, (2008) (PubMed).

Lee, Paik, Kang, Lim, Kim: "Allelic variants interaction of CLOCK gene and G-protein beta3 subunit gene with diurnal preference." in: Chronobiology international, Vol. 24, Issue 4, pp. 589-97, (2007) (PubMed).

Moreira, Pedrazzoli, Dos Santos Coelho, Pradella-Hallinan, Lopes da Conceição, Pereira Peregrino, de Oliveira, Tufik: "Clock gene polymorphisms and narcolepsy in positive and negative HLA-DQB1*0602 patients." in: Brain research. Molecular brain research, Vol. 140, Issue 1-2, pp. 150-4, (2005) (PubMed).

Muñoz, Brewer, Baler: "Circadian Transcription. Thinking outside the E-Box." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36009-17, (2002) (PubMed).

Synonyms and alternative names related to CLOCK

Clock (Clk), clock circadian regulator (CLOCK), clock homolog (mouse) (CLOCK), clock circadian regulator (clock), clock circadian regulator a (clocka), circadian locomotor output cycles kaput (Clock), clock circadian regulator (Clock), clock circadian regulator L homeolog (clock.L), 5330400M04Rik, bHLHe8, bHLHe10, CG7391, CLK, clk, CLOCK, clock, dClck, dCLK, dClk, dclk, dCLK/JRK, dCLOCK, dClock, Dmel\\CG7391, Jerk, Jrk, jrk, KAT13D, mKIAA0334, PAS1, Xclk, XClock, zCLOCK1, zfCLOCK1

Protein level used designations for CLOCK

  • CG7391-PA
  • CG7391-PD
  • CG7391-PF
  • CG7391-PG
  • CG7391-PH
  • CLOCK
  • Clk-PA
  • Clk-PD
  • Clk-PF
  • Clk-PG
  • Clk-PH
  • clock
  • dClock
  • clock homolog (mouse)
  • clock homolog
  • circadian locomoter output cycles protein kaput
  • circadian locomoter output cycles protein kaput-like
  • Clock1a
  • clk1
  • circadian locomoter output cycles kaput
  • mCLOCK
  • rCLOCK
  • circadian locomoter output cycles kaput protein
  • class E basic helix-loop-helix protein 8
  • circadian rhythmicity protein CLOCK
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