CLK1 产品
(CDC like Kinase 1 (CLK1))
Categories
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
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Featured CLK1 Categories
Recommended CLK1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7186348
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (2)
- (3)
Cat. No.
ABIN2784736
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7150730
Quantity
100 μL
Datasheet
Datasheet
Recommended CLK1 ELISA试剂盒
Recommended CLK1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (2)
Cat. No.
ABIN5569791
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5569679
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349700
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CLK1 Products
: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).
: "Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation." in: PLoS ONE, Vol. 8, Issue 3, pp. e59137, (2013) (PubMed).
: "Regulation and substrate specificity of the SR protein kinase Clk/Sty." in: Molecular and cellular biology, Vol. 23, Issue 12, pp. 4139-49, (2003) (PubMed).
: "Alternative splicing of STY, a nuclear dual specificity kinase." in: The Journal of biological chemistry, Vol. 270, Issue 37, pp. 21524-31, (1995) (PubMed).
Synonyms and alternative names related to CLK1
CDC like kinase 1 (CLK1), CDC-like kinase 1 (Clk1), CLK, CLK/STY, STYProtein level used designations for CLK1
- CDC28/CDC2-like kinase
- dual specificity protein kinase CLK1
- protein tyrosine kinase STY
- protein kinase STY
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