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CLEC12A 产品

(C-Type Lectin Domain Family 12, Member A (CLEC12A))
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011].

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Featured CLEC12A Categories

CLEC12A 抗体

High quality antibodies with extensive validation data.

CLEC12A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CLEC12A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLEC12A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
Cat. No. ABIN7193253
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN7193252
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7146051
Quantity 100 μL
Datasheet Datasheet

Recommended CLEC12A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1124428
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730635
Quantity 96 tests
Datasheet Datasheet

Recommended CLEC12A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274358
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274346
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274353
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CLEC12A Products

Hutten, Thordardottir, Fredrix, Janssen, Woestenenk, Tel, Joosten, Cambi, Heemskerk, Franssen, Boerman, Bakker, Jansen, Schaap, Dolstra, Hobo: "CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2715-25, (2016) (PubMed).

Neumann, Castiñeiras-Vilariño, Höckendorf, Hannesschläger, Lemeer, Kupka, Meyermann, Lech, Anders, Kuster, Busch, Gewies, Naumann, Groß, Ruland: "Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death." in: Immunity, Vol. 40, Issue 3, pp. 389-99, (2014) (PubMed).

Synonyms and alternative names related to CLEC12A

C-type lectin domain family 12 member A (CLEC12A), C-type lectin domain family 12, member a (Clec12a), C-type lectin domain family 12, member A (Clec12a), CLL-1, CLL1, D230024O04, DCAL-2, KLRL1, MGC179455, MICL, Micl

Protein level used designations for CLEC12A

  • C-type lectin domain family 12, member A
  • C-type lectin domain family 12 member A
  • C-type lectin protein CLL-1
  • C-type lectin superfamily
  • C-type lectin-like molecule-1
  • dendritic cell-associated lectin 2
  • myeloid inhibitory C-type lectin-like receptor
  • C-type lectin-like molecule 1
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