The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008].
custom-made
CKM
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
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Trask, Strauss, Billadello: "Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene." in: The Journal of biological chemistry, Vol. 263, Issue 32, pp. 17142-9, (1988) (PubMed).
Perryman, Kerner, Bohlmeyer, Roberts: "Isolation and sequence analysis of a full-length cDNA for human M creatine kinase." in: Biochemical and biophysical research communications, Vol. 140, Issue 3, pp. 981-9, (1986) (PubMed).