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抗Human MEOX1 抗体:
抗Mouse (Murine) MEOX1 抗体:
抗Rat (Rattus) MEOX1 抗体:
Human Polyclonal MEOX1 Primary Antibody for WB - ABIN1881549
Petropoulos, Gianakopoulos, Ridgeway, Skerjanc: Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cells. in The Journal of biological chemistry 2004
study reveals the molecular basis for a novel somite lineage restriction mechanism (controlled by meox1) and defines a new paradigm in induction of definitive hematopoietic stem cells
The G > A p.Q84X mutation in the MEOX1 is identified in Klippel-Feil syndrome (显示 GDF6 抗体).
We describe a multiplex consanguineous family in which isolated KFS (显示 GDF6 抗体) maps to a single 17q21.31 locus that harbors a homozygous frameshift deletion in MEOX1; this deletion results in complete instability of the transcript
The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 (显示 PBX1 抗体) in ovarian cancers.
No mutations were identified in the PAX1 (显示 PAX1 抗体) and MEOX1 exons or flanking intronic sequences, excluding them as likely causative genes for diaphanospondylodysostosis
MEOX1 and MEOX2 (显示 MEOX2 抗体) activate p16(INK4a (显示 CDKN2A 抗体)) in a DNA binding dependent manner, whereas they induce p21(CIP1/WAF1 (显示 CDKN1A 抗体)) in a DNA binding independent manner.
Meox1 expression is downregulated in the second arch of Hoxa2 (显示 HOXA2 抗体) mouse mutant embryos.
Results demonstrate that Meox1 and Meox2 (显示 MEOX2 抗体) genes function together and upstream of several genetic hierarchies that are required for the development of somites.
Data show that Meox1 activates the Bapx1 (显示 NKX3-2 抗体) promoter in a dose-dependent manner and that this activity is enhanced in the presence of Pax1 (显示 PAX1 抗体) and/or Pax9 (显示 PAX9 抗体).
Meox and Gli (显示 GLI1 抗体) have roles in skeletal myogenesis
Data sugges that Meox1 is part of a regulatory circuit that serves an essential, non-redundant function in the maintenance of rostro-caudal (显示 CAD 抗体) sclerotome polarity and axial skeleton formation.
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.
Mox-1 related protein
, homeobox protein MOX-1
, mesenchyme homeo box 1
, mesenchyme homeobox 1
, Homeobox protein MOX-1