CHRFAM7A 抗体
(CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10) and FAM7A (Family with Sequence Similarity 7A, Exons A-E) Fusion (CHRFAM7A))
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CHRFAM7A 抗体 (AA 124-174) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 124-174
Latest Publications for our CHRFAM7A 抗体
: "Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 144B, Issue 5, pp. 611-4, (2007) (PubMed).
: "Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway." in: Cancer research, Vol. 64, Issue 1, pp. 135-45, (2004) (PubMed).
: "Endothelial-leukocyte adhesion molecules in inflammation and metastasis." in: Thrombosis and haemostasis, Vol. 70, Issue 1, pp. 152-4, (1993) (PubMed).
: "Granular cell basal cell carcinoma. Light microscopy, immunohistochemical and ultrastructural study." in: Virchows Archiv. A, Pathological anatomy and histopathology, Vol. 422, Issue 2, pp. 173-7, (1993) (PubMed).
: "Expression of selectin ligands by cutaneous squamous cell carcinoma." in: The American journal of pathology, Vol. 143, Issue 4, pp. 1220-5, (1993) (PubMed).
: "Comparative immunohistochemical study of primary and metastatic carcinomas of the liver." in: American journal of clinical pathology, Vol. 99, Issue 5, pp. 551-7, (1993) (PubMed).
: "Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer." in: Cancer, Vol. 71, Issue 10, pp. 3044-53, (1993) (PubMed).
: "Apocrine carcinoma of the skin. A clinicopathologic, immunocytochemical, and ultrastructural study." in: Cancer, Vol. 71, Issue 2, pp. 375-81, (1993) (PubMed).
: "Expression of the CD15 antigen in hepatocellular carcinoma." in: Cancer, Vol. 71, Issue 12, pp. 3864-7, (1993) (PubMed).
: "Adhesive interactions in angiogenesis and metastasis." in: Pharmacology & therapeutics, Vol. 53, Issue 2, pp. 239-60, (1992) (PubMed).
: "Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway." in: Cancer research, Vol. 64, Issue 1, pp. 135-45, (2004) (PubMed).
: "Endothelial-leukocyte adhesion molecules in inflammation and metastasis." in: Thrombosis and haemostasis, Vol. 70, Issue 1, pp. 152-4, (1993) (PubMed).
: "Granular cell basal cell carcinoma. Light microscopy, immunohistochemical and ultrastructural study." in: Virchows Archiv. A, Pathological anatomy and histopathology, Vol. 422, Issue 2, pp. 173-7, (1993) (PubMed).
: "Expression of selectin ligands by cutaneous squamous cell carcinoma." in: The American journal of pathology, Vol. 143, Issue 4, pp. 1220-5, (1993) (PubMed).
: "Comparative immunohistochemical study of primary and metastatic carcinomas of the liver." in: American journal of clinical pathology, Vol. 99, Issue 5, pp. 551-7, (1993) (PubMed).
: "Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer." in: Cancer, Vol. 71, Issue 10, pp. 3044-53, (1993) (PubMed).
: "Apocrine carcinoma of the skin. A clinicopathologic, immunocytochemical, and ultrastructural study." in: Cancer, Vol. 71, Issue 2, pp. 375-81, (1993) (PubMed).
: "Expression of the CD15 antigen in hepatocellular carcinoma." in: Cancer, Vol. 71, Issue 12, pp. 3864-7, (1993) (PubMed).
: "Adhesive interactions in angiogenesis and metastasis." in: Pharmacology & therapeutics, Vol. 53, Issue 2, pp. 239-60, (1992) (PubMed).
Aliases for CHRFAM7A 抗体
CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion (CHRFAM7A) 抗体CHRNA7 抗体
CHRNA7-DR1 抗体
D-10 抗体
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