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Chloride Channel 5 产品

(Chloride Channel 5 (CLCN5))

Categories

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013].

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Featured Chloride Channel 5 Categories

Chloride Channel 5 抗体

High quality antibodies with extensive validation data.

Chloride Channel 5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Chloride Channel 5 抗体

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Application WB
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Cat. No. ABIN2776081
Quantity 100 μL
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Reactivity Human, Mouse, Rat
Application IHC, IF
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Cat. No. ABIN7073471
Quantity 100 μL
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Cat. No. ABIN1881207
Quantity 400 μL
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Recommended Chloride Channel 5 蛋白

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Source Wheat germ
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Cat. No. ABIN1776894
Quantity 10 μg
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Source Wheat germ
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Cat. No. ABIN1349571
Quantity 10 μg
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN3077705
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Latest Publications for our Chloride Channel 5 Products

Hryciw, Jenkin, Simcocks, Grinfeld, McAinch, Poronnik: "The interaction between megalin and ClC-5 is scaffolded by the Na?-H? exchanger regulatory factor 2 (NHERF2) in proximal tubule cells." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 5, pp. 815-23, (2012) (PubMed).

Ceol, Tiralongo, Baelde, Vianello, Betto, Marangelli, Bonfante, Valente, Della Barbera, DAngelo, Anglani, Del Prete: "Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies." in: PLoS ONE, Vol. 7, Issue 9, pp. e45605, (2012) (PubMed).

Smith, Lippiat: "Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3696-705, (2010) (PubMed).

Wellhauser, DAntonio, Bear: "ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 2, pp. 543-57, (2010) (PubMed).

Picollo, Malvezzi, Accardi: "Proton block of the CLC-5 Cl-/H+ exchanger." in: The Journal of general physiology, Vol. 135, Issue 6, pp. 653-9, (2010) (PubMed).

White: "On the position and value of those Lesions of the Brain which cause a rise of Temperature." in: The Journal of physiology, Vol. 12, Issue 3, pp. 233-298.3, (2007) (PubMed).

Moulin, Igarashi, Van der Smissen, Cosyns, Verroust, Thakker, Scheinman, Courtoy, Devuyst: "Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients." in: Kidney international, Vol. 63, Issue 4, pp. 1285-95, (2003) (PubMed).

Claverie-Martin, González-Acosta, Flores, Antón-Gamero, García-Nieto: "De novo insertion of an Alu sequence in the coding region of the CLCN5 gene results in Dent's disease." in: Human genetics, Vol. 113, Issue 6, pp. 480-5, (2003) (PubMed).

Jouret, Igarashi, Gofflot, Wilson, Karet, Thakker, Devuyst: "Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5." in: Kidney international, Vol. 65, Issue 1, pp. 198-208, (2003) (PubMed).

Synonyms and alternative names related to Chloride Channel 5

chloride voltage-gated channel 5 (CLCN5), chloride channel, voltage-sensitive 5 L homeolog (clcn5.L), chloride channel, voltage-sensitive 5 (clcn5), chloride channel, voltage-sensitive 5 (Clcn5), chloride voltage-gated channel 5 (Clcn5), 5430408K11Rik, ClC-5, Clc5, CLC5, CLCK2, CLCN3, CLCN4, CLCN5, Clcn5, clcn5-A, D930009B12Rik, DENTS, DKFZp469O2315, DXImx42e, hCIC-K2, NPHL1, NPHL2, Sfc13, T25545, XLRH, XRN

Protein level used designations for Chloride Channel 5

  • chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease)
  • chloride channel protein 5
  • chloride channel 5
  • H(+)/Cl(-) exchange transporter 5-like
  • Chloride channel protein 5
  • H(+)/Cl(-) exchange transporter 5
  • chloride transporter ClC-5
  • voltage-gated chloride ion channel CLCN5
  • clC-5
  • chloride channel CLC-5
  • chloride channel CLCN5
  • chloride channel Clc-5
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