CDC42BPA 抗体
(CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008].
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Latest Publications for our CDC42BPA 抗体
: "Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake." in: Biochemical and biophysical research communications, Vol. 395, Issue 2, pp. 163-7, (2010) (PubMed).: "Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation." in: European journal of cell biology, Vol. 81, Issue 4, pp. 231-42, (2002) (PubMed).
: "Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha." in: Molecular and cellular biology, Vol. 21, Issue 8, pp. 2767-78, (2001) (PubMed).
: "Characterization of a monoclonal antibody panel shows that the myotonic dystrophy protein kinase, DMPK, is expressed almost exclusively in muscle and heart." in: Human molecular genetics, Vol. 9, Issue 14, pp. 2167-73, (2000) (PubMed).
: "Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10013-20, (1997) (PubMed).
Aliases for CDC42BPA 抗体
CDC42 binding protein kinase alpha (CDC42BPA) 抗体CDC42 binding protein kinase alpha (Cdc42bpa) 抗体
GDNF family receptor alpha 2 (GFRA2) 抗体
serine/threonine-protein kinase MRCK alpha (LOC100182779) 抗体
CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA) 抗体
serine/threonine-protein kinase MRCK alpha (LOC100545977) 抗体
A930014J19Rik 抗体
CDC42BPA 抗体
DMPK-like 抗体
MRCK 抗体
Mrck 抗体
MRCKA 抗体
PK428 抗体
Pk428 抗体
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