CDC25A 抗体
(Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our CDC25A 抗体
: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).: "Silencing CDC25A inhibits the proliferation of liver cancer cells by downregulating IL‑6 in vitro and in vivo." in: International journal of molecular medicine, Vol. 45, Issue 3, pp. 743-752, (2020) (PubMed).
: "Regulation of Signaling Pathways Involved in the Anti-proliferative and Apoptosis-inducing Effects of M22 against Non-small Cell Lung Adenocarcinoma A549 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 992, (2018) (PubMed).
: "Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways." in: The Science of the total environment, Vol. 589, pp. 97-106, (2017) (PubMed).
: "A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in ..." in: Mutation research, Vol. 777, pp. 79-90, (2015) (PubMed).
: "Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
: "A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk." in: Oncogene, (2015) (PubMed).
: "Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 5, pp. 761-71, (2015) (PubMed).
: "CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute." in: Oncogene, Vol. 31, Issue 4, pp. 403-18, (2012) (PubMed).
: "An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis." in: International journal of oncology, Vol. 40, Issue 6, pp. 2131-9, (2012) (PubMed).
Aliases for CDC25A 抗体
cell division cycle 25A (CDC25A) 抗体cell division cycle 25A (cdc25a) 抗体
cell division cycle 25B (cdc25b) 抗体
cell division cycle 25A (Cdc25a) 抗体
cell division cycle 25A S homeolog (cdc25a.S) 抗体
cdc25A 抗体
cdc25a2 抗体
CDC25A2 抗体
D9Ertd393e 抗体
sb:cb317 抗体
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