CD47 蛋白
(CD47)
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CD47 Protein (CD47) (AA 19-139) (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 19-139) (His tag) | 人 | 人细胞 |
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| CD47 Protein (CD47) (AA 19-141) (His tag) | Cynomolgus | 人细胞 |
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| CD47 Protein (CD47) (AA 19-139) (His tag) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 10-131) (Fc Tag) | 猕猴 | 人细胞 |
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| CD47 Protein (CD47) (AA 19-139) (Fc Tag) | Cynomolgus | 人细胞 |
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| CD47 Protein (CD47) (AA 19-139) (mFc Tag) | 人 | 人细胞 |
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| CD47 Protein (CD47) (AA 19-141) (DYKDDDDK-His Tag) | 猕猴 | 人细胞 |
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| CD47 Protein (CD47) (Fc Tag) | 大鼠 | HEK-293 Cells |
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| CD47 Protein (CD47) (Fc Tag,His tag) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 19-139) (hFc-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 19-140) (hFc Tag) | 大鼠 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 19-139) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (His tag) | 人 | Mammalian Cells |
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| CD47 Protein (CD47) (AA 19-158) (His tag) | 小鼠 | Mammalian Cells |
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| CD47 Protein (CD47) (AA 19-141) (hIgG-His-tag) | 人 | Baculovirus infected Insect Cells |
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| CD47 Protein (CD47) (AA 19-141) (His tag) | 人 | Baculovirus infected Insect Cells |
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| CD47 Protein (CD47) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (DYKDDDDK Tag,Strep Tag) | 人 | HEK-293 Cells |
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| CD47 Protein (CD47) (AA 19-141) (Fc Tag) | Cynomolgus | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 人细胞
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- ELISA (ELISA: 所列应用)
- Imm (Immunogen: 所列应用)
- cryo-EM (Cryogenic electron microscopy: 所列应用)
- PhD (Phage Display: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Synthetic Nanodisc
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Latest Publications for our CD47 蛋白
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
: "Cancer immunotherapy targeting the CD47/SIRPα axis." in: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).
: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
: "Cancer immunotherapy targeting the CD47/SIRPα axis." in: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).
Aliases for CD47 蛋白
alkaline phosphatase, intestinal (ALPI) 蛋白CD47 molecule (CD47) 蛋白
CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47) 蛋白
Cd47 molecule (Cd47) 蛋白
9130415E20Rik 蛋白
AA407862 蛋白
AI848868 蛋白
AW108519 蛋白
B430305P08Rik 蛋白
CD47/IAP 蛋白
IAP 蛋白
Itgp 蛋白
MER6 蛋白
OA3 蛋白
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