CD46 蛋白
(CD46)
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
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27 results
CD46
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
CD46
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
1 image
CD46
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD46
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, ELISA, Imm, AcA
Active
CD46
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
SDS, WB, Imm, PC
CD46
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
CD46
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
CD46
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
CD46
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Latest Publications for our CD46 蛋白
: "Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions." in: Nature communications, Vol. 10, Issue 1, pp. 741, (2019) (PubMed).: "CD46 facilitates entry and dissemination of human cytomegalovirus." in: Nature communications, Vol. 10, Issue 1, pp. 2699, (2019) (PubMed).
: "C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cells." in: Virus research, Vol. 179, pp. 231-4, (2014) (PubMed).
: "Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?" in: Journal of neuroimmunology, Vol. 276, Issue 1-2, pp. 172-4, (2014) (PubMed).
Aliases for CD46 蛋白
CD46 molecule (CD46) 蛋白CD46 antigen, complement regulatory protein (Cd46) 蛋白
CD46 molecule (Cd46) 蛋白
CD46 molecule, complement regulatory protein (CD46) 蛋白
membrane cofactor protein-like (LOC100341359) 蛋白
membrane cofactor protein-like (LOC103789310) 蛋白
AHUS2 蛋白
CD46 蛋白
MCP 蛋白
Mcp 蛋白
MIC10 蛋白
TLX 蛋白
TRA2.10 蛋白
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