CD33 抗体
(CD33)
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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Latest Publications for our CD33 抗体
: "Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 121, pp. 70-75, (2019) (PubMed).: "In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia." in: Molecular cancer therapeutics, Vol. 15, Issue 10, pp. 2422-2431, (2016) (PubMed).
: "miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells." in: International journal of oncology, Vol. 48, Issue 4, pp. 1737-48, (2016) (PubMed).
: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." in: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, (2015) (PubMed).
: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." in: Transplantation, Vol. 99, Issue 4, pp. 668-77, (2015) (PubMed).
: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1270, (2015) (PubMed).
: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).
: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).
: "The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo." in: Cell death & disease, Vol. 4, pp. e973, (2013) (PubMed).
: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." in: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).
Aliases for CD33 抗体
CD33 molecule (CD33) 抗体CD33 antigen (Cd33) 抗体
CD33 molecule (Cd33) 抗体
gp67 抗体
p67 抗体
SIGLEC-3 抗体
Siglec-3 抗体
SIGLEC3 抗体
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