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CD276 抗体

(CD276)
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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  • 抗原: CD276
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7876480
CD276 抗体 (AA 7-3, AA 100-300) CD276 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 B7H3-4479
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 100 μg
发货至: 中国
Primary Antibody
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
质量等级
Carrier-free
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
B7H3-4479
标记
unconjugated
抗体亚型
IgG1, kappa
抗原表位
AA 100-300, AA 7-3
产品编号 ABIN7876480

Latest Publications for our CD276 抗体

Zhang, Wang, Marzese, Wang, Yang, Li, Zhang, Zhang, Chen, Kelly, Hua, Hoon, Mao: "B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma." in: Laboratory investigation; a journal of technical methods and pathology, (2019) (PubMed).

Shi, Ma, Cao, Zhan, Xu, Fu, Liu, Zhang, Wang, Wang, Lu, Lu, Chen, Zhang: "B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2." in: Cell death & disease, Vol. 10, Issue 4, pp. 308, (2019) (PubMed).

Wilson, Bachawal, Abou-Elkacem, Jensen, Machtaler, Tian, Willmann: "Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent." in: Theranostics, Vol. 7, Issue 6, pp. 1463-1476, (2018) (PubMed).

Hock, MacPherson, McKenzie: "Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0172858, (2017) (PubMed).

Li, Guo, Song, Cai, Yang, Chen, Wang, Huang, Gao: "B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway." in: Journal of Cancer, Vol. 8, Issue 5, pp. 816-824, (2017) (PubMed).

Quandt, Fiedler, Müller, Marsch, Seliger: "High constitutive B7-H3 expression on human keratinocytes supports T cell immunity." in: Journal of dermatological science, Vol. 87, Issue 1, pp. 82-85, (2017) (PubMed).

Yoon, Chung, Yoo, Kawara, Kim, Yoo, Park, Kang, Lee: "Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis." in: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4048-57, (2016) (PubMed).

Bachawal, Jensen, Wilson, Tian, Lutz, Willmann: "Breast Cancer Detection by B7-H3-Targeted Ultrasound Molecular Imaging." in: Cancer research, Vol. 75, Issue 12, pp. 2501-9, (2015) (PubMed).

Sucker, Zhao, Real, Heeke, Bielefeld, Maβen, Horn, Moll, Maltaner, Horn, Schilling, Sabbatino, Lennerz, Kloor, Ferrone, Schadendorf, Falk, Griewank, Paschen: "Genetic evolution of T-cell resistance in the course of melanoma progression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 24, pp. 6593-604, (2014) (PubMed).

Lemke, Pfenning, Sahm, Klein, Kempf, Warnken, Schnölzer, Tudoran, Weller, Platten, Wick: "Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 1, pp. 105-17, (2012) (PubMed).

Aliases for CD276 抗体

CD276 molecule (CD276) 抗体
CD276 molecule S homeolog (cd276.S) 抗体
CD276 molecule (cd276) 抗体
CD276 antigen (Cd276) 抗体
Cd276 molecule (Cd276) 抗体
4Ig-B7-H3 抗体
6030411F23Rik 抗体
AU016588 抗体
B7-H3 抗体
B7h3 抗体
B7H3 抗体
B7RP-2 抗体
sc:d0645 抗体
zgc:158279 抗体
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