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CD22 抗体

(CD22 Molecule (CD22))
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins\; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

225 results

CD22 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal CBO-3 unconjugated
产品编号 ABIN7604309
 
CD22 适用: 人 WB 宿主: 小鼠 Monoclonal 5E7 unconjugated
产品编号 ABIN7602740
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 Biotin
产品编号 ABIN6182041
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®594
产品编号 ABIN6182036
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®568
产品编号 ABIN6182026
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®647
产品编号 ABIN6182020
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®405S
产品编号 ABIN6182012
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 Biotin
产品编号 ABIN6182003
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®594
产品编号 ABIN6181998
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®488A
产品编号 ABIN6181996
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®647
产品编号 ABIN6181982
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®640R
产品编号 ABIN6181978
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®405S
产品编号 ABIN6181974
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®488A
产品编号 ABIN6182034
 
CD22 适用: 人 FACS, WB, ELISA, IHC, IF, Coat 宿主: 小鼠 Monoclonal BLCAM-1795 CF®640R
产品编号 ABIN6182016
 
CD22 适用: 人, 小鼠, 大鼠 FACS, IF 宿主: 小鼠 Monoclonal Myg13 CF®568
产品编号 ABIN6181988
 
CD22 适用: 人 FACS, WB, IF 宿主: 小鼠 Monoclonal BLCAM-1796 CF®640R
产品编号 ABIN7651002
 
CD22 适用: 人 FACS, WB, IF 宿主: 小鼠 Monoclonal BLCAM-1796 CF®405S
产品编号 ABIN7651000
 
CD22 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal RFB4 CF®405S
产品编号 ABIN7650999
 
CD22 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal RFB4 CF®640R
产品编号 ABIN7651001
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Flow Cytometry (FACS)
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Functional Studies (Func)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Coating (Coat)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
    • Immunomicroscopy (IM)
    • Blocking Antibody (Inhibition)
    • Surface Plasmon Resonance (SPR)
    • Bio-Layer Interferometry (BLI)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Staining Methods (StM)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Monkey
    • Non-Human Primate
    • Dog
    • Primate
    • Horse
  • 论文引用
  • 图像
  • 仅无防腐剂
  • Carrier free only
  • 抗体来源
    • Mouse
    • Rabbit
    • Rat
    • Human
  • 克隆形成能力
    • Monoclonal
    • Polyclonal
    • Chimeric
  • 克隆
    • Cy34-1
    • MYG13
    • BLCAM-1796
    • RFB4
    • BLCAM-1795
    • 2D6
    • MEM-01
    • Myg13
    • C2
    • C29
    • C32
    • C15
    • FR10B4
    • IS7
    • 2H1C4
    • 3D8
    • 3H4
    • B-ly8
    • C14
    • C6
    • OX-97
    • 10C3
    • 14i97
    • 1A3A11
    • 1F12
    • 2E6
    • 3H1116
    • 4C3
    • 5E7
    • 5K249
    • BLR214K
    • BU59
    • CBO-3
    • DM13
    • DM14
    • G12H9
    • G544
    • LL2
    • MSVA-022R
    • NCIm971
    • NCIm972
    • OTI1E6
    • OTI2B12
    • RFB-4
  • 抗原表位
    • AA 52-178
    • pTyr807
    • AA 28-246
    • C-Term
    • AA 20-400
    • AA 621-725
    • N-Term
    • AA 20-687
    • AA 707-847
    • Domain 2
    • AA 708-847
    • AA 750-830
    • AA 146-343
    • AA 176-330
    • AA 45-94
    • AA 656-670
    • AA 696-724
    • AA 701-847
    • AA 758-807
    • AA 773-822
    • AA 776-825
    • AA 839-843
    • Extracellular Domain
    • Heavy Chain
    • Ser214
    • Tyr807
    • pTyr1150
    • pTyr1151
    • pTyr762
    • pTyr822
    • pTyr842
  • 标记
    • 非结合性
    • Biotin
    • PE
    • FITC
    • APC
    • CF®740
    • CF®405S
    • CF®488A
    • CF®568
    • CF®594
    • CF®640R
    • CF®647
    • Alexa Fluor 488
    • Elab Fluor®700
    • PE-Cy5
    • Alexa Fluor 647
    • Magnetic Particles
    • PE-Cy7
    • PerCP-Cy5.5
    • Sepharose
    • APC-iFluor™700
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • PE,Cy5
    • PE-Cy5.5
    • SPRD
    • mFluor™450
  • 抗体亚型
    • IgG1
    • IgG
    • kappa
    • IgG1 kappa
    • IgG2b
    • IgG2a
    • IgG2b kappa
    • IgG kappa
    • IgG4
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • GMP Grade
    • GMP Grade (Analyte)
  • Supplier
    • antibodies-online
    • Biotium
    • Biomatik
    • USBio
    • Elabscience
    • Signalway
    • Acris
    • Boster Bio
    • Covalab
    • Aviva Systems Biology
    • Cloud-Clone
    • OriGene
    • ProSci
    • RayBiotech
    • Abbexa
    • Aeonian Biotech
    • Assay Biotechnology Company, Inc.
    • NSJ Bioreagents

Latest Publications for our CD22 抗体

Lennon, Cao, Hall, Vickers, Barker: "The red blood cell as a novel regulator of human B-cell activation." in: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).

Kreimann, Jang, Rong, Greite, von Vietinghoff, Schmitt, Bräsen, Schiffer, Gerstenberg, Vijayan, Dittrich-Breiholz, Wang, Karsten, Gwinner, Haller, Immenschuh, Gueler: "Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation." in: Frontiers in immunology, Vol. 11, pp. 1204, (2020) (PubMed).

Ljungars, Svensson, Carlsson, Birgersson, Tornberg, Frendéus, Ohlin, Mattsson: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).

Jelicic, Cimbro, Nawaz, Huang, Zheng, Yang, Lempicki, Pascuccio, Van Ryk, Schwing, Hiatt, Okwara, Wei, Roby, David, Hwang, Kehrl, Arthos, Cicala, Fauci: "The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression." in: Nature immunology, Vol. 14, Issue 12, pp. 1256-65, (2013) (PubMed).

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Tuscano, Kato, Pearson, Xiong, Newell, Ma, Gandara, ODonnell: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).

Kawasaki, Rademacher, Paulson: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).

Yu, Li, Li, Zang, Liu: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).

Duong, Ota, Aït-Azzouzene, Aoki-Ota, Vela, Huber, Walsh, Gavin, Nemazee: "Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4143-58, (2010) (PubMed).

Walker, Smith: "CD22: an inhibitory enigma." in: Immunology, Vol. 123, Issue 3, pp. 314-25, (2008) (PubMed).

Aliases for CD22 抗体

CD22 antigen (Cd22) 抗体
CD22 molecule (CD22) 抗体
CD22 molecule (Cd22) 抗体
A530093D23 抗体
Lyb-8 抗体
Lyb8 抗体
SIGLEC-2 抗体
siglec-2 抗体
SIGLEC2 抗体
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