CD22 抗体
(CD22 Molecule (CD22))
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins\; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CD22 抗体 (pTyr807) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CD22 抗体 | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (Biotin) | 人, Non-Human Primate | 小鼠 Monoclonal |
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| Recombinant CD22 抗体 | 人 | 兔 Monoclonal |
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| CD22 抗体 | 小鼠 | 大鼠 Monoclonal |
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| CD22 抗体 (C-Term) | 人 | 小鼠 Monoclonal |
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| Recombinant CD22 抗体 | 人 | Human Monoclonal |
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| CD22 抗体 | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (FITC) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (AA 701-847) | 人 | 兔 Polyclonal |
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| CD22 抗体 (AA 28-246) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (FITC) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (APC) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (APC-iFluor™700) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (mFluor™450) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (FITC) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (PE) | 人 | 小鼠 Monoclonal |
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| CD22 抗体 (N-Term) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr807
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, Non-Human Primate
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MEM-01
- 标记
- Biotin
- 抗体亚型
- IgG1
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB3365
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- Act (Activation: 所列应用)
1 reference - 适用
- 小鼠
- 宿主
- 大鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2D6
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8265
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- C-Term
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- ELISA (ELISA: 所列应用)
- Func (Functional Studies: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- BLI (Bio-Layer Interferometry: 所列应用)
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- NCIm971
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- IFA (Indirect Immunofluorescence Assay: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- RFB4
- 标记
- FITC
- 抗体亚型
- IgG1
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 701-847
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- C2
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 28-246
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MYG13
- 标记
- FITC
- 抗体亚型
- IgG1, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MYG13
- 标记
- APC
- 抗体亚型
- IgG1, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade (Analyte)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MYG13
- 标记
- APC-iFluor™700
- 抗体亚型
- IgG1, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- GMP Grade (Analyte)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- MYG13
- 标记
- mFluor™450
- 抗体亚型
- IgG1, kappa
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-ly8
- 标记
- FITC
- 抗体亚型
- IgG1
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- B-ly8
- 标记
- PE
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Latest Publications for our CD22 抗体
: "The red blood cell as a novel regulator of human B-cell activation." in: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).
: "Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation." in: Frontiers in immunology, Vol. 11, pp. 1204, (2020) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
: "The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression." in: Nature immunology, Vol. 14, Issue 12, pp. 1256-65, (2013) (PubMed).
: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).
: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).
: "Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4143-58, (2010) (PubMed).
: "CD22: an inhibitory enigma." in: Immunology, Vol. 123, Issue 3, pp. 314-25, (2008) (PubMed).
: "Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation." in: Frontiers in immunology, Vol. 11, pp. 1204, (2020) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
: "The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression." in: Nature immunology, Vol. 14, Issue 12, pp. 1256-65, (2013) (PubMed).
: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).
: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).
: "Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4143-58, (2010) (PubMed).
: "CD22: an inhibitory enigma." in: Immunology, Vol. 123, Issue 3, pp. 314-25, (2008) (PubMed).
Aliases for CD22 抗体
CD22 antigen (Cd22) 抗体CD22 molecule (CD22) 抗体
CD22 molecule (Cd22) 抗体
A530093D23 抗体
Lyb-8 抗体
Lyb8 抗体
SIGLEC-2 抗体
siglec-2 抗体
SIGLEC2 抗体
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