CD1b 抗体
(CD1b (CD1B))
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008].
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Latest Publications for our CD1b 抗体
: "Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200564, (2018) (PubMed).: "Summary of the animal homologue section of HLDA8." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 2-13, (2007) (PubMed).
: "Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis." in: Infection and immunity, Vol. 75, Issue 11, pp. 5210-22, (2007) (PubMed).
: "Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction." in: Journal of virology, Vol. 79, Issue 5, pp. 3009-15, (2005) (PubMed).
: "Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6229-38, (2004) (PubMed).
: "Human macrophage lectin specific for galactose/N-acetylgalactosamine is a marker for cells at an intermediate stage in their differentiation from monocytes into macrophages." in: International immunology, Vol. 14, Issue 6, pp. 545-54, (2002) (PubMed).
: "The in vivo development of human T cells from CD34(+) cells in the murine thymic environment." in: International immunology, Vol. 14, Issue 10, pp. 1113-24, (2002) (PubMed).
: "The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 6, pp. 3780-8, (2001) (PubMed).
: "The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 4, pp. 2562-70, (2001) (PubMed).
: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).
Aliases for CD1b 抗体
CD1b molecule (CD1B) 抗体T-cell surface glycoprotein CD1b-3 (LOC443423) 抗体
CD1b1 molecule (CD1B1) 抗体
T-cell surface glycoprotein CD1b1 (LOC100720602) 抗体
CD1 抗体
CD1-b 抗体
CD1A 抗体
CD1B 抗体
CD1B3 抗体
R1 抗体
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