CD160 抗体
(CD160)
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008].
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Latest Publications for our CD160 抗体
: "Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1838-48, (2015) (PubMed).: "CD160 isoforms and regulation of CD4 and CD8 T-cell responses." in: Journal of translational medicine, Vol. 12, pp. 217, (2015) (PubMed).
: "Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses." in: PLoS ONE, Vol. 9, Issue 2, pp. e88327, (2014) (PubMed).
: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
: "BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells." in: Clinical and experimental immunology, Vol. 149, Issue 1, pp. 87-96, (2007) (PubMed).
: "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 6, pp. 2780-90, (1998) (PubMed).
: "BY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 19, pp. 9136-40, (1994) (PubMed).
Aliases for CD160 抗体
CD160 molecule (CD160) 抗体CD160 molecule (Cd160) 抗体
CD160 antigen (Cd160) 抗体
AU045688 抗体
BY55 抗体
By55 抗体
CD160 抗体
NK1 抗体
NK28 抗体
RGD1563598 抗体
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