The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012].
Pierog, Krishna, Yamniuk, Chauhan, DeSilva: "Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples." in: Journal of immunological methods, Vol. 416, pp. 124-36, (2015) (PubMed).
Aliases for CD16 蛋白
Fc fragment of IgG, low affinity IIa, receptor (Fcgr2a) 蛋白 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A) 蛋白 Fc fragment of IgG receptor IIIb (FCGR3B) 蛋白 Fc fragment of IgG receptor IIIa (FCGR3A) 蛋白 Fc receptor, IgG, low affinity III (Fcgr3) 蛋白 Fc-gamma RIII (FCGR3) 蛋白 CD16 蛋白 CD16b 蛋白 FCG3 蛋白 Fcgr3 蛋白 FCGR3 蛋白 FCGR3@ 蛋白 Fcgr3a 蛋白 FCR-10 蛋白 FCRIII 蛋白 FcRIII 蛋白 FCRIIIb 蛋白