CCR1 抗体
(Chemokine (C-C Motif) Receptor 1 (CCR1))
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008].
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Latest Publications for our CCR1 抗体
: "A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis." in: Oncotarget, Vol. 7, Issue 36, pp. 57705-57713, (2018) (PubMed).: "Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain." in: Molecular immunology, Vol. 77, pp. 184-92, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling." in: Journal of leukocyte biology, Vol. 98, Issue 3, pp. 395-407, (2015) (PubMed).
: "IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 5, pp. 2099-109, (2015) (PubMed).
: "TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity." in: Cancer research, Vol. 75, Issue 10, pp. 1959-71, (2015) (PubMed).
: "NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation." in: Genome biology, Vol. 16, pp. 2, (2015) (PubMed).
: "CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells. ..." in: PLoS ONE, Vol. 9, Issue 8, pp. e105883, (2015) (PubMed).
: "Mechanisms by which chronic ethanol feeding impairs the migratory capacity of cutaneous dendritic cells." in: Alcoholism, clinical and experimental research, Vol. 37, Issue 12, pp. 2098-107, (2013) (PubMed).
: "Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes." in: EMBO molecular medicine, Vol. 5, Issue 3, pp. 471-81, (2013) (PubMed).
Aliases for CCR1 抗体
C-C motif chemokine receptor 1 (CCR1) 抗体chemokine (C-C motif) receptor 1 (Ccr1) 抗体
C-C motif chemokine receptor 1 (Ccr1) 抗体
CD191 抗体
CKR-1 抗体
CKR1 抗体
CMKBR1 抗体
Cmkbr1 抗体
HM145 抗体
Mip-1a-R 抗体
MIP1aR 抗体
SCYAR1 抗体
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