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CBFB 蛋白

(Core-Binding Factor, beta Subunit (CBFB))
The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

9 results :

custom-made CBFB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7550641
 
custom-made CBFB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7556918
 
CBFB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1348164
 
CBFB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7417792
 
CBFB 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7418203
 
CBFB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2128359
 
custom-made CBFB 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3121502
 
custom-made CBFB 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3085782
 
CBFB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713253
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • 抗原表位
    • AA 1-182
    • AA 1-187
    • Transcript Variant 2
  • 标记
    • His tag
    • Strep Tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene

Aliases for CBFB 蛋白

core-binding factor beta subunit (CBFB) 蛋白
core binding factor beta subunit (Cbfb) 蛋白
core-binding factor, beta subunit (cbfb) 蛋白
core-binding factor, beta subunit (Cbfb) 蛋白
core-binding factor, beta subunit S homeolog (cbfb.S) 蛋白
core binding factor beta (Cbfb) 蛋白
core-binding factor beta subunit (Cbfb) 蛋白
AI893578 蛋白
cbf-beta 蛋白
Cbfb 蛋白
CBFB 蛋白
cbfbeta 蛋白
PEA2 蛋白
pea2-beta 蛋白
Pebp2 蛋白
pebp2-beta 蛋白
PEBP2B 蛋白
pebp2b 蛋白
PEBP2b 蛋白
Pebpb2 蛋白
unp1266 蛋白
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